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Furthermore, variants will be mapped against a list of brain-expressed genes determined by expression array analysis across 57 postmortem brains and multiple brain regions in a recent study of the human brain transcriptome throughout development and adulthood [ 49].
The current study shows that Endo180 expression is negligible in the normal brain but highly upregulated in GBMs as revealed by expression array analysis and immunohistochemical staining of patient material.
Several studies have subdivided GBMs by expression array analysis measuring total cellular mRNA levels.[14] [19] However, because of differential translational efficiencies, total mRNA levels do not always correlate with protein levels.
These findings are consistent with those in subtypes defined by expression array analysis [ 3].
The changes in our EMT markers are in the order of 1.13 to 1.19 fold of control by expression array analysis.
We first searched for candidate tumor suppressor genes by expression array analysis, focusing on genes with more decreased expression levels in HCC tissue than adjacent noncancerous tissue.
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In addition, we examined a functional role for UBF1/2 in mediating Pol II transcription by performing expression array analysis in control and UBF1/2 depleted NIH3T3 cells.
To try and discern the pathways involved in cell death induction by BN108, expression array analysis (Methods S1) was performed with RNAs isolated from BT474 cells prior to and after a 4 hour treatment with BN108.
By gene expression array analysis, we found that forced expression of WT1 had a regulatory function on many known WT1 target genes.
Here we extend investigations of the processes downstream of en by using expression array analysis to compare A and P cells.
The populations of five ulcer tissues (4, 12, 13, 14, 15) and five non-ulcer tissues (4 ni, 12 ni, 13 ni, 14 ni, 15 ni) were compared by GeneChip expression array analysis ("ulcus-vs-ni").
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