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However, the vast majority of lost edges would not be easy to identify just by exploring the expression values of their TFs or targets genes.
We further characterized the role of Rfx6 downstream of Ngn3 by exploring the expression levels of several important transcription factors controlling islet cell fate and maturation.
This network analysis can help to recognize patterns that were not visible by exploring the expression data alone and help to illustrate the conserved and unique patterns across the stages of LUAD.
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In the present study we tried to provide a preliminary answer to this question by systematically exploring the expression level of a large set of breast cancer related gene signatures derived from human tumors in samples from dog mammary tumors.
By exploring the differential expression profiles, our correlation-based strategy can reveal the synergistic effects of drug combinations.
Following our previous study in genetic dissection of rhizomatousness in O. longistaminata, we report here an effort to understand the molecular mechanisms of tissue specificity in O. longistaminata by exploring the genome-wide gene expression patterns.
In a related article, Jonsson et al. [ 2] adopted a more direct approach by exploring the clinical relevance of immunohistochemical expression of a member of the Wnt family, Wnt-5a, in primary invasive carcinomas.
Previous work by Ückert et al (2001, 2006) explored the expression of PDE families in the histological zones of the prostate by using RT PCR, immunofluorescence and selective PDE inhibitors.
Accordingly we explored the expression level of differentiation associated genes by RT-qPCR.
This study attempted to address some of the gaps in our knowledge, by exploring mRNA expression profiles following BCG vaccination of newborns.
In the present study, we sought potential tumour suppressor genes by exploring gene expression differences between primary NB tumours with favourable or unfavourable biology from a Swedish patient group.
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