In this study, we designed a set of assemblage-specific primers by exploiting sequence variability in homologous genes from assemblages A, B and E. Primers were designed to amplify fragments of different size that generated different melting curves from each assemblage in real-time PCR (rt-PCR) experiments.
We show that highly selective PDE4B inhibitors can be designed by exploiting sequence differences outside the active site.
A comparative sequence analysis, exploiting sequence information from various resources, can be used to uncover hidden information, such as genetic variation.
In this report, we have taken an approach for describing positioned nucleosomes, which exploits sequence information derived from the periodic occurrences of the 256 tetranucleotides in nucleosome DNA.
Second, in this study, we considered only simple statistical estimators for the optimal sequencing depth; however, more elaborate approaches are possible, e.g., by exploiting the results from the fitted growth curves.
For this purpose, a training sequence is inserted within the main data, which enables the receiver to obtain the output of the channel by exploiting this training sequence.
The added value of a custom repeat collection comes from the isolation of target sequences by exploiting all of their fundamental features – i.e. existing in a high copy number, possessing typical sequence motifs, and/or encoding for specific domains.
SLA maps original vibration data from rotating machinery to a binary symbolic sequence by exploiting potential of increase and decreases of time intervals.
By exploiting the dynamical information from big data, a novel biomarker, DNB, was recently developed [22].
By exploiting the ORF/protein predictions from ESTScan, we also investigated the position of the SSRs along the transcripts.
