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A pathophysiological role for cross-reactivity of anti-dsDNA Abs with extracellular α-actinin in vivo, however, is not supported by experimental models for LN.
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This factor is also strongly suggested by experimental models [ 46].
Progress has been limited by the lack of established experimental models for studying leprosy-induced neuropathy.
However, up to now few pre-clinical studies directly addressed the role played by psychosocial factors and provided validated experimental models for human stress-induced metabolic disorders, which are very common, for example, in several psychiatric conditions [1], [4], [8] [12].
Unfortunately, there is a lack of experimental models for ML caused by Leishmania species other than L. braziliensis complex.
PG-116800 is a member of the hydroxyproline-based hydroxamic acid class of MMP inhibitors which has been shown to inhibit the joint damage caused by iodoacetate injection into rat knees, an experimental model for OA [ 24].
In 1989, Portha et al. developed an experimental model for testing insulin resistance by administering streptozotocin to newly born rats.
And it is now to be an experimental model for how public services more widely could be run.
Yes… and this is supported by metabolic and experimental models.
Just as for experimental models in biology, relative predictions by in silico models may be more useful than absolute predictions.
This contention is supported by a number of experimental models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com