Sentence examples for by exogenous expression of from inspiring English sources

However, a critical control, rescue of phenotypes in ATG16L1*300A-expressing cells from patients by exogenous expression of ATG16L1*300T, is likely to be challenging due to technical limitations.

Engineering of Pt/HPt dependency required disruption of all endogenous P transporters supplemented by exogenous expression of PtxD and a P transport system that takes up Pt/HPt but not Pi.

This growth arrest can be rescued by exogenous expression of the fusion and a mutant designed to prevent translation of the ELK4 protein.

This suppression can be rescued by exogenous expression of wild-type FMRP but not by its nucleosome-binding-deficient mutant T102A or Y103L.

These results may be caused by exogenous expression of MEK2.

Therefore, we tested the activity of the antibody on signaling induced by exogenous expression of Wnt3a and other Wnt isoforms.

A similar restorative effect was observed by the exogenous expression of ASK1 wild-type or even by that of kinase-negative mutant in ASK1-deficient MEFs.

By contrast, exogenous expression of WT DUSP6 reduced basal levels of pATM foci by ∼50%.

Similarly, ORCA associates with Suv39h1, and this interaction is not affected by the exogenous expression of FL or Ankyrin-G9a.

We are also providing two new sets of endogenous IP data to demonstrate that ORCA associates with G9a and that this interaction is not affected by the exogenous expression of FL-and SET 151-412 -Suv39H11. 151-412 -Suv39H1

Systematic search for genes whose gain-of-function by exogenous expression confers an advantage in cell-based selective screenings is a powerful method for unbiased functional exploration of the genome, and has the potential to disclose new targets for cancer therapy.