Sentence examples for by excessive expression of from inspiring English sources

It is proposed that this imbalance is characterized by excessive expression of RAR- α and reduced expression of RAR- β.

At the receptor level, it is proposed that this imbalance is characterized by excessive expression of retinoic acid receptor-α (RARα) and reduced expression of retinoic acid receptor-β (RARβ).

Chitin patch caused less inflammation by inhibiting excessive expression of IL-6 and TNF-α when compared to the polypropylene mesh (P < 0.01).

Finally, it is of course possible that the pathway is not activated in a cell-autonomous manner by oncogenic mutations, but that excessive expression of Wnt ligands could account for the nuclear β-catenin staining seen in tumor biopsies and could contribute to tumor development in vivo.

Excessive expression of adhesion molecules by RASFs facilitates the attachment of RASFs to the adjacent cartilage and bone, leading to joint destruction, and excessive expression of chemokines by RASFs facilitates the influx of inflammatory cells.

The current work is the first to demonstrate the direct association of CD11a overexpressed on SSc CD4+ T cells with excessive expression of COL1A2 by fibroblasts, a considerably important process in the pathogenesis of SSc.

Another significant finding showed that EGCG, the chief polyphenol of green tea, attenuated the excessive expression of CTGF induced by abdominal aortic constriction (AAC) or AngII and also showed role in the reduction of nuclear translocation of NF- κB p65 subunit and degradation of I κB- α [ 67].

Excessive expression of these metalloproteinases induced by S. aureus could lead to the destruction of the soft tissue connective tissue architecture.

The excessive expression of miR-21 induced by transfection of miR-21 completely eliminated cardamonin's action and showed a higher proliferation above its basal level (stimulated by VEGF).

Pro-inflammatory cytokines are involved in the pathogenesis of many inflammatory diseases, and the excessive expression of many of them is normally counteracted by glucocorticoids (GCs), which are steroids that bind to the glucocorticoid receptor (GR).

A harmful effect of excessive expression of Hsp70 on fitness was also observed by Krebs and Feder [56], [57].