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Next, we asked what the effects of ME2 depletion would be in vivo by examining tumorigenicity of K562 cells in mice.
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We next examined tumorigenicity of vaccine-exposed GL26, as enhanced tumorigenicity is a consistently reported property of GSCs.
We examined tumorigenicity in immunodeficient mice.
Despite this well-described cellular state, this is the first report examining the tumorigenicity of reovirus PI or cured cancer cells.
We examined the tumorigenicity of A0, A1, and A2 cells by injecting the cells into Balb/c nude mice.
Next, we examined the tumorigenicity of BRAT1 knockdown cells in vivo by xenograft assay using HeLa Sh3 and Sh8 cells.
One study used, PC3, an aggressive androgen-independent human prostate cancer cell line, to examine in vivo tumorigenicity of Pim1.
Recently, we showed that p48 acts as an oncogene by promoting tumorigenicity of glioma cells through the downregulation of p53.
Further, TTF1 cDNA was introduced into BHP18-21v cells, which are human PTC cells, to examine the effects of TTF1 on tumorigenicity of these cells.
The mechanism by which IL6 affects the tumorigenicity of these bladder carcinoma cell lines remains unclear.
To further evaluate the enhancement of tumorigenicity of LC-CD133+, we examined in vitro Matrigel-combined Transwell invasion and soft agar colony formation assays.
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