Exact(13)
HVEM-deficient lymphoma B cells also induce a tumor-supportive microenvironment marked by exacerbated lymphoid stroma activation and increased recruitment of T follicular helper (TFH) cells.
Indeed, genes implicated very early in the regulatory mechanisms of the response to septic shock could become high medical value biomarkers allowing individualized treatments aimed at restricting the dysfunctions induced by exacerbated or uncontrolled inflammation.
The aggravated clinical course of arthritis was accompanied by exacerbated synovial inflammation and bone erosion.
Mild chronic cerebral hypoperfusion caused a general dysfunction in brain capillaries, which was characterized by exacerbated IgG entrapment in these capillaries.
The precise cause of the ill health is unknown; however, perturbed intestinal epithelial barrier dysfunction, which is in part characterized by exacerbated villae apoptosis, could cause similar phenotypes.
A selective vulnerability of posterior segments was evident by exacerbated morphological defects at synaptic terminals and dystonic posterior paralysis (tail-flip phenotype) (Fuger et al. 2012).
Similar(47)
Clinical studies, discussed below, are also identifying a rapidly growing number of conditions that are precipitated by or exacerbated loss of functions by astrocytes or reactive astrocytes.
While inhibition of Hsp70 by VER155008 exacerbated neuroinflammatory response in astrocytes challenged by α-Syn aggregates.
In septic shock, the low counts in circulating ILC3 s could be explained by ILC plasticity (conversion of these cells into ILC1 s), by migration from the blood or by an exacerbated apoptosis.
Inhibition of autophagy flux by chloroquine exacerbated Mn-induced cytotoxicity, while induction of autophagy by rapamycin significantly reduced cell death caused by Mn.
In contrast, knockdown of HRG by siRNA exacerbated lethality.
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