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This study explored this hypothesis by evaluating the functional overlap of the signatures on the basis of annotated gene sets.
By evaluating the functional behavior of mice receiving pain/miR23b, normal/anti-miR23b, anti-miR23b/si-NOX4, pain/NOX4 antibody, pain/ascorbic acid, and pain/ascorbic acid/NOX4 antibody, the positive role of miR23b and the negative role of NOX4 in neuropathic pain were confirmed.
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One of the problems raised by next-generation sequencing is evaluating the functional significance of newly identified rare variants.
Simultaneous chlorophyll fluorescence and 820 nm transmission measurements by using М-РЕА-2 allow evaluating the functional state of PSII and PSI.
The Ka/Ks ratios were also used for evaluating the functional divergence by the C value test [ 52].
To further address this question we plan to test the effect of rapamycin on animals with established tumors (by measuring tumor growth) along with evaluating the functional status of mTOR and the ability of rapamycin to suppress it in tumors and normal tissues.
The global chemical character of complex chemical fuel mixtures is explicitly determined by evaluating the abundances of chemical functional groups present within them rather than by applying a traditional interpretation based upon molecular species composition.
This metabolic alteration is intricately linked to cancer progression.The aim of this work has been to demonstrate the possibility of differentiating a neoplastic cell toward different germ layer lineages, by evaluating the morphological, metabolic and functional changes occurring in this process.
We can see decreased image intensities in the joints from the treatment group in comparison with the measurements from the non-treatment group, suggesting that, by evaluating the angiogenesis in arthritic tissues, the functional information presented by PAI can help monitoring the treatment efficacy.
The importance of individual genes within these functional groups was identified by evaluating the regression coefficients of the genes.
Next, we examined the effect of Rab21 mutation on fluid-phase uptake by macropinocytosis to evaluate the functional implication of its GTP binding and GTP hydrolysis in macropinosome formation.
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