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However, both Fold-X and AutoDock vina evaluate the Ca2+-protein affinity essentially by estimating interactions of Ca2+ with the atoms of the protein lining the binding pocket.
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Before modification of the initial network, we estimated interaction parameters of the initial network by use of maximum likelihood estimation.
Once we classify the areas, we can interpret the variability by looking at the time profiles of the estimated interactions.
This table shows the changes (after minus before) in the outcomes in intervention and control trusts and the effects of implementing the CPOE system as the relative increase or decrease in each outcome (estimated by interactions of implementation and period in the regression models), adjusted for underlying trends in all trusts.
Finally, we address the issue of interactions between mantle plumes and the lithosphere by estimating the depth of the lithosphere asthenosphere boundary (LAB).
The estimated interaction effects between PBD and state unemployment rates on job finding by ineligible individuals raise the possibility of similar interaction effects for eligible individuals.
PBPK modeling to simulate potential exposures may offer an opportunity to increase the specificity without losing the sensitivity by estimating exposures under conditions of drug drug interaction and other situations rather than using the mean efficacious therapeutic level.
This relevant question can first be tackled by estimating the consumption rate of gold precursors within the volume of interaction.
We tested the proportional hazard assumption by estimating alternative specifications that admitted interactions between analysis time and variables of interest.
The interactive effect by psychiatric history was estimated by including the interaction of COPD and psychiatric history in the adjusted model for the total and for each specific sex and age group.
Estimates of interaction of diagnosis by septic category, diagnosis by time, and diagnosis by septic category by time were not significant predictors (data not shown).
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