Furthermore, by engineering a high-producing industrial strain via tandem deletion of GBL receptor genes, validamycin production and productivity were enhanced from 19 to 24 g/L (by 26%) and from 6.7 to 9.7 g L−1 d−1 (by 45%), respectively, which was the highest ever reported.
We have been able to increase the yield of the affinity purification step by engineering a tag with higher affinity.
To facilitate genetic improvement of Camelina, a developing seed transcriptome was recently generated, and its utility was demonstrated by its use for engineering a high oleic acid oil trait for improved oil oxidative stability [ 2 ].
To manipulate the oil composition of organisms of choice, by a metabolic engineering approach, a high expression level of the ∆-desaturase enzyme in a heterologous host is required.
By engineering electrodes of accommodating high volume expansion, we demonstrate a prototype to achieve high performance batteries, especially high-power batteries.
In one of the few exceptions, overexpression of human erythropoietin in mammalian cells was shown to be influenced by engineering to contain human (high G+C) or yeast (high A+T) optimized codons, although expression levels differed by only 2.5-fold [42].
We have determined the crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach.
High Voc approaching band gap energy is expected if one can reach the theoretical Voc deficit by engineering perovskite layer with highest internal PL quantum yield.
Commercial production can also be accomplished by improving the genetic engineering strategies to control environmental stress conditions and by engineering metabolic pathways for high lipid production.
However, it is severely impacted by civil engineering, which causes a high level of amphibian mortality.
