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By enabling the simultaneous monitoring of a large set of metabolites in cirrhotic patients with HE, CSF metabolomics highlighted several altered metabolite pathways linked to ammonia metabolism, neurotransmission and energy metabolism.
It will add further efficiency and versatility to the study of cellular communication by enabling the simultaneous monitoring of different gene expression patterns in cells in coculture.
In addition to the detection of known ALK gene fusions, targeted resequencing holds a great advantage over other methods by enabling the simultaneous screening of novel ALK fusion partners as well as other lung cancer-related gene mutations, fusions and copy number alterations, saving time and material in the long run.
It was concluded that use of this pipeline could at least halve the time taken for future genetic marker development in kiwifruit, by enabling the simultaneous screening of several thousand markers over population phenotype extremes, compared with the previous requirement to screen genome-wide markers individually.
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The major recent advances of omics technologies are now enabling the simultaneous measurement of millions of biochemical entities.
Starting with gold nanoparticles as a core, layer-by-layer degradable polymer coatings enable the simultaneous co-delivery of DNA and short interfering RNA (siRNA).
The assessment of regional myocardial function by this new method enables the simultaneous analysis of its radial and longitudinal components.
The addition of another prism inclining its polarizing axis by π/4 against the first one enables the simultaneous measurement of optical rotations based on the PPD at many wavelengths.
An additional benefit of this co-culture system (not provided by transient assays) is that it enables the simultaneous analysis of multiple, endogenous PERV elements, which are precisely the targets one would want to monitor and ideally inhibit in (xeno transplantation procedures.
Here we show that pulse-chase analysis followed by laser ablation electrospray ionization mass spectrometry (LAESI-MS) enable the simultaneous and rapid determination of metabolic turnover rates.
This microarray platform enables the simultaneous analysis of all human microRNAs by either fluorescent or electrochemical signals, and can be easily redesigned to include newly identified miRNAs.
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