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Prior work has demonstrated decreased urokinase activity in the air spaces of patients with ALI/ARDS, and this decrease is explained by elevations in levels of PAI-1 [ 8].
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It is recognised that the porcine APP response to infection is typically characterised by elevations in serum levels of C-reactive protein as the major APP [14].
The reduction in serum IGF-1 levels in the iLID mice were accompanied by elevations in serum GH levels, which were detectable at the age of sacrifice (Figure 2D).
This protective process is substantiated in M. arctica by elevations in the expression levels of the desaturase gene and TPS (also reflected in biochemical studies [ 12]).
The process of myocardial tissue necrosis is accompanied by elevations in enzyme serum levels of CPK, AST, LDH, and troponin due to myocardial cellular damage.
A substantial number of patients with end-stage chronic renal failure (CRF) on dialysis have an inflammatory state that can be detected by elevation in serum levels of C-reactive protein (CRP).
Many inflammatory diseases, as well as infections, are accompanied by elevation in cellular levels of Reactive Oxygen Species (ROS).
We hypothesized that if bone marrow lesions are areas of accelerated bone turnover, then they should be accompanied by elevation in systemic levels of bone turnover markers.
Unlike systemic inflammation, which developed principally in critically ill patients, intensive CNS inflammation (reflected by elevation in cytokine levels and immune cell counts) was universally present in EV71-infected patients, accompanied by CNS disease.
The emergence of core promoter mutations during the immune clearance phase of infection, as indicated by elevations in Alanine transaminase (ALT) levels, is consistent with a physiological significance of reducing HBeAg expression.
Precipitating migraine in susceptible individuals by administration of nitroglycerin causes elevations in levels of CGRP in the jugular venous blood, although it should be noted that inhibiting CGRP does not block nitroglycerin-induced migraine.
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