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Conversely, reduction of Mps1 activity has recently been shown to sensitize tumor cells but not normal cells to low doses of taxol by elevating the frequency of chromosome missegregations to near-lethal levels [17].
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A recent study from our lab proposed that elevating the frequency of chromosome segregation errors by partial Mps1 reduction can be of clinical relevance, especially with other treatments that affect fidelity of chromosome segregation [17].
This means that by elevating the sales experience for women, you're elevating it for all of your customers.
Indeed, it has been shown that over-expression of RAD51 elevates the frequency of gene targeting [7], [23].
As expected, depletion of BLM in HeLa cells markedly elevated the frequency of SCE.
Shifting your focus to gratitude elevates the frequency at which your body, mind and spirit vibrate.
Brown Recluse Esq.: I liked "Elevating the Game" by Nelson George.
Although many studies have found that CRISPR/Cas9 technology is more efficient, specific and manipulable than previous generations of gene editing tools, it can be further improved by elevating its overall efficiency in a higher frequency of genome modifications and reducing its off-target effects.
Over-nutrition and obesity can elevate the incidence and frequency of physiological insults by stimulating TORC1 activity [ 47], which in turn accelerates anabolic metabolism [ 16, 17].
Thus, the identification of any factor that elevates the basal mutation frequency is a high priority.
In chordamesodermal cells with little protrusive activity, the intracellular calcium was not elevated with high frequency (data not shown).
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