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Exact(17)
Skin injury by either agent alone was quantitated by the probability of tail necrosis as a function of dose of agent.
Each effect was greater than that evoked by either agent alone, indicating enhanced efficacy for therapeutic approaches that target multiple, distinct mechanism of telomere maintenance.
The decrease in Bcl2/Bax ratio in neurons exposed to both Tat and morphine was greater than what was induced by either agent alone.
Combined exposure of Tat and morphine in SHSY5Y cells led to a dramatic increase in ROS generation, which was significantly higher than the ROS levels generated by either agent alone.
This amplified death above that induced by either agent alone reflected activation through both the extrinsic (DR; Ashkenazi, 2008) and intrinsic (fenretinide; Myatt et al, 2005) apoptotic pathways.
A summary of these results indicates that epithelial and inflammatory responses to coexposure of these two pollutants are greater than those elicited by either agent alone.
Similar(43)
Dual infection of pigs with PCV2 and PRRSV has consistently resulted in more severe disease than that caused by infection with either agent alone [ 29, 31, 32].
Combination of the two agents showed a better pro-apoptosis effect than either agent alone by using the annexin V/propidium iodide staining (Fig. 2C) and the DNA content analysis (Fig. 2D).
Clearance of NHL cells from ascites in scid mice is prolonged by the combination, as compared with either agent alone.
In both cases, a substantial number of genes are reactivated by the combination more so than either agent alone, resulting in greater anti-leukemic activity.
In addition, saxagliptin metformin therapy produced significant improvements in β-cell function (based on HOMA-2β assessment, compared with saxagliptin [ P < 0.0001] or metformin [ P ≤ 0.0004] alone), numerically greater increases in postprandial insulin compared with metformin alone, and in early insulin response measured by the insulinogenic index compared with either agent alone.
More suggestions(15)
by either hypoxia alone
by either cytokine alone
by either intervention alone
by either mutation alone
by either compound alone
by either substance alone
by either method alone
by either inhibitor alone
by either cue alone
by either molecule alone
by either approach alone
by either drug alone
by either component alone
by either platform alone
by either botezomib alone
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com