Clinical cure is a subjective outcome that was defined by each study's authors, and potentially subject to bias, given that the studies were mainly unblinded [ 94], and the microbiologic causes of infections were different, and appropriateness of empiric antibiotics, a key determinant of outcomes, was not reported.
When calculating the effect on inequalities, we examined the primary outcome of interest for each intervention as identified by the study author.
Some diseases, like cancer and HIV/AIDS, get funded at better rates than predicted based on the disease burden, while others like stroke and depression fall short, according to an analysis by study author Hamilton Moses III of Alerion Advisors.
These specimens were originally discovered and collected in South Africa by study author Roger Smith, but when Kammerer was visiting the museum collections there he noticed some unexpected traits in some of the dicynodont fossils.
§Cardiac disease as defined by study author.
The primary endpoint was cardiovascular events (myocardial infarction, stroke, and cardiovascular mortality, or as defined by study author).
Note also that when we identify significant differences, we are referring to statistically significant differences identified by the original study authors, each of whom established a relevant α-value for their study populations.
Judgements on quality were informed by limitations explicitly reported by study authors in the included studies.
