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After ranking pairs by each method, we constructed Precision-Recall (PR) curves.
To compare the individual cell size deletion strains identified by each method, we first defined two-step filters for significant enrichment or depletion by barcode.
From the probabilities estimated by each method, we calculated the overall probabilities that each haplotype originates from line 1.
Although there were some differences in the exact positions identified by each method, we observed similar trends overall.
Then, for the nodes in the G t estimated by each method, we computed (i) degree and (ii) clustering coefficient CC) profiles over time.
To explore the overlap among the significant pathways identified by each method, we compared four result sets and drew a Venn diagram.
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By comparing (AUC+AUPRC /2 score of each method, we discover that normalization methods designed for mRNA data that tend to be overly aggressive (e.g., quantile normalization) provide virtually no additional benefits in recovering truly differentially expressed features.
To further investigate the effectiveness of each method, we draw by different methods the phylogenetic trees of 20 bacterial species selected randomly which are a subset of the dataset 1 in Table 1. Figure 8 shows four phylogenetic trees inferred by the GCD, CVTree, ComPhy, and CGCPhy methods.
We also examined the distribution of the lengths of the IBD segments identified by each method and we considered computation time.
To characterize the function of genes that were classified differently by each method (Class B), we analyzed their expression patterns in the vegetative growth phase and their promoter sequences.
For each trial identified by this method, we used the international standard randomised controlled trial number registry (isrctn.org), ClinicalTrials.gov registry, PubMed, Google, and manual evaluation of references to search for other reports from that trial published until end of April 2013.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com