The mechanism by which duplicate genes originate – whether by duplication of a whole genome or of a genomic segment – influences their genetic fates.
However, SSD implies the deletion of one of the duplicates generated by WGD, followed by duplication of the remaining copy, as we only considered gene pairs.
The four clusters of Hox genes found in mammals originated by duplication of the whole original cluster and retain considerable similarity between clusters.
Further delays were caused by duplication of stages, slide labelling, batching and inappropriate quality control.
A greater variety of error types were detected by Mendelian-inheritance error checking than by duplication of saMendelian-inheritance errornalysis of gels.
This finding, coupled with the observation that this complete set of genes exists in all flagella-bearing bacteria, suggests the genes arose by duplication of a single gene in the ancestor of all bacteria, Ochman says.
These results indicate that transgenic integration of the tgε26 allele is accompanied by duplication of a 323 kb genomic region between the Sstr5 and Metrn loci (Fig. 2L).
FLT3-ITDs are formed by duplication of a fragment in the juxtamembrane domain that is always in frame but varies in length.
Members of the Ugt2 family are clustered in one locus in human, mouse and rat, and are probably evolved by duplication of the entire gene [14].
Therefore we speculated that transgenic insertion in the tgε26 allele is accompanied by duplication of the neighboring genomic region, as previously demonstrated in other transgenic mice [10] [13].
Our phylogenetic analysis (figure 1) supports an origin of ParaHox genes by tandem duplications, in agreement with Ryan et al. [37], rather than by duplication of an ancestral "ProtoHox" cluster (figure 4A).
