Sentence examples for by driving the expression from inspiring English sources

Collective results from the present study demonstrate that endogenous vagal afferent signaling from the GI tract regulates HPC-dependent contepisodicpisodic and spatial working memory, potentially by driving the expression of memory-related neurotrophic (BDNF) and neurogenic (DCX) signaling pathways.

This gene has been shown to be frequently downregulated in malignant gliomas and to regulate invasiveness of some glioma cell lines [1] by driving the expression of matrix metalloproteinases through the ERK 1/2 pathway.

An EP screen for potential new PCP components was performed by driving the expression of several EP collections on the notum of the adult fly using the apterous-Gal4 driver.

The specific promoters of Ath5 used in the transgenic lines allow to visualize developing retinal ganglion cells (RGCs) with their optic nerve axons by driving the expression of green (GFP) and red fluorescent protein (RFP) respectively (Figure 4A and B, [11]).

In contrast to classical in vivo "knockout" strategies, which result in a complete deletion of gene function in the whole organism, this conditional gene targeting technology enables a cell type-specific deletion of genes by driving the expression of Cre recombinase under the control of a cell type-specific promoter [1], [5], [6].

We examine the specific requirement of Ppt1 in neurons by driving the expression of Ppt1-RNAi in strains containing the ds RNA-GD3286 cobtained (obtained from the Vienna Drosophila RNAi Center [24]); and the dsRNA-JF01972 construct from the TriP-1 collection (Bloomington Drosophila Stock Center) using various neural-specific Gal4 drivers (Bloomington Drosophila Stock Center).

To understand which one of the two putative responsive elements found in the " in-silico" analysis is physically bound by OTX2, driving the expression of TAp63, we performed a ChIP analysis using chromatin of transfected cells pulled down using OTX antibody.

EGFP was cloned downstream of the retroviral LTR promoter followed by the CD40L promoter driving the expression of HcRed (Clontech) with the small t-intron and polyadenylation sequence from SV40 (Fig. 2a).

Nrf2 is a transcription factor that responds to oxidative and thiol stress by binding AREs and driving the expression of multiple antioxidant and anti-inflammatory target genes including heme oxygenase 1 (HMOX1), NAD(P H dehydrogenase (quinone) (NQO1) and glutathione peroxidase (GPX4) (27, 27).

Hsp response can be used to detect toxicants in the cellular environment by engineering cells with DNA constructs driving the expression of a reporter protein under the control of an hsp promoter.

The construct containing the antioxidant response element (ARE) sequences driving the expression of luciferase was kindly supplied by Dr. J.A. Johnson (University of Wisconsin, Madison, WI, USA) [23].