Thus, drift and selection by dosage eventually drives some duplicates towards fixation while others turn into pseudogenes.
Kaizu, K., Moriya, H. & Kitano, H. Fragilities caused by dosage imbalance in regulation of the budding yeast cell cycle.
Reed, S.I., Hadwiger, J.A., Richardson, H.E. & Wittenberg, C. Analysis of the Cdc28 protein kinase complex by dosage suppression.
Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, et al. Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial.
These effects were mediated by dosage alterations of RUNX1, ETS2, and ERG, which are located in a critical 4-Mb region of chromosome 21.
A process evaluation found high-quality implementation of the OH strategy as measured by dosage, fidelity, and caregiver reactions to implementing the strategy.
Completion rates by dosage groups were 47.3% for the 1 mg group, 58.2% for the 2 mg group and 70.9% for the 4 mg group (χ2=12.7, df=2, P=0.0017).
Table 2 shows that the operating costs were deeply influenced by dosage of chemicals and the needed irradiation time.
Plasma HBP was also positively correlated with severity of shock as indicated by dosage of noradrenaline and plasma lactate concentrations at days 1 4 (see Additional file 2: Figure S1 for day 1 data).
The presence of anaerobic organism in the leachate sample at ratio 1 15 (100 mL) could remove up to 42 % of the COD concentration followed by dosage of 75 mL (1 20) and 100 mL (1 15), respectively.
It is possible that the diverse function of auxin may be explained by dosage effects and/or other factors that are likely involved.
