While it is possible to reduce the volume of ER+ tumors by inhibiting the production of estrogen it is important to consider that estrogen plays an integral role in the normal physiology of women by controlling diverse processes such as cholesterol production and maintenance of bone density [ 6].
Methylation of nucleosomal histones by PRMTs plays an important role in diverse processes such as nuclear receptor-mediated transcriptional regulation or chromatin remodeling.
Even if the disease were set in motion by a single genetic factor, its aetiology would involve many diverse processes such that DD will be co-determined by the many factors that regulate those processes.
Several of these proteolytic enzymes may be involved in diverse processes such as signal transduction, extracellular matrix processing and immunity.
Secreted Wnt ligands bind Frizzled receptors to regulate diverse processes such as axis patterning, cell division, and cell fate specification.
Diverse processes, such as the response to pathogens or wounding but also leaf senescence, are controlled by WRKY transcription factors (Rushton et al., 2010).
DNA methylation is essential to diverse processes such as development, X-inactivation, and imprinting [ 3- 5].
NFAT5 has been implicated in diverse processes such as embryonic development, cellular migration, and proliferation.
Complement is involved in diverse processes, such as angiogenesis, inflammation, tissue injury, and regeneration.
In lymphocytes, LFA-1 is important for diverse processes such as migration, antigen presentation or cytotoxicity.
