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Because shared databases often contain data owned by both the archivists and collaborating investigators, special privileges by distinct classes of users should be avoided but if required should be explicitly legislated and declared.
Some of these features include exonic and intronic enhancer and silencer elements, which are recognized by distinct classes of RNA-binding proteins [14].
The mammalian brain is characterized by distinct classes of cells that differ in morphology, structure, signaling, and function.
Regulation of NK cell activity requires a tight balance between activating and inhibitory signals, which is mediated by distinct classes of receptors on the cell surface.
These results suggest that systemically administered KOP receptor agonists produce antinociception through a stress-induced mechanism, which can be blocked by distinct classes of anxiolytics, including DOP receptor agonists.
Phosphorylation of ETS proteins by distinct classes of MAPK, including ERK, JNK, and p38, can alter transcriptional functions by various mechanisms including changing DNA affinity [ 8], increasing co-activator recruitment or activity [ 9, 10], or altering subcellular localization [ 11, 12].
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In mammals, the UPR is transduced by three distinct classes of ER transmembrane proteins: PERK, ATF6 and Ire1p homologues [ 27].
Estrogen may activate or repress transcription of ER target genes potentially by recruiting distinct classes of co-regulators that have chromatin remodeling properties.
Vertebrate chemoreception is made possible by six distinct classes of multi-transmembrane receptors: (i) olfactory receptors (ORs) [ 5], (ii) trace amine-associated receptors [ 6], vomeronasal receptors (iii) type 1 and (iv) type 2 [ 7, 8] and taste receptors (v) type 1 and (vi) type 2 [ 9, 10].
In contrast with other insect orders such as Lepidoptera [ 38- 41] and Diptera [ 6, 7, 21] in which the evolution of the sex chromosomes has been studied by mapping distinct classes of DNAs, there is a complete lack of knowledge at the molecular level concerning the evolution of the neo-sex chromosomes in grasshoppers and the mechanisms that underlie the degeneration of the neo-Y chromosome.
These findings suggested the possibility that increased expression of specific ribosomal proteins in unique tissues might lead to the heterogeneous ribosomes in the distinguished cell tissues by specificities in translating distinct classes of mRNAs.
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Justyna Jupowicz-Kozak
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