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Fusions may drive oncogenic growth by joining a proliferation-inducing gene to an active promoter, by disrupting the function of tumor suppressor genes, or by creating novel functional products that rewire the biochemical pathways that regulate cellular division [ 1].
Taxanes act by disrupting the function of the microtubules.
This is meant to stimulate diversification by disrupting the function of utilizing one distinct resource.
Alcohol causes fetal alcohol spectrum disorders in part by disrupting the function of the neural cell adhesion molecule L1.
Alcohol exposure during pregnancy may cause fetal alcohol spectrum disorders, in part, by disrupting the function of the neural cell adhesion molecule L1.
As the mutant RalAQ72L is constitutively in a GTP-bound form in the cells, not mediated by GEF, the results again suggested that RILP inhibits the activation of RalA by disrupting the function of GEF in RalGDS.
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Oxidants may also confer susceptibility to other pathogenic processes by disrupting the functions of cytoprotective proteins, such as metabolic enzymes and cell membrane transporters [7].
As we proposed artemisinin inhibits malaria by disrupting the normal function of malarial mitochondria, we tested the idea whether the synthetic peroxide trioxolanes may also affect mitochondrial function.
Pyrethroids act on the nervous system by disrupting the normal function of voltage-gated sodium channels (VGSCs), which control the influx of sodium ions into neurons to transmit nerve signals.
It has been reported that many viral immune evasion genes are considered as "stolen" mimics from the host and such viruses may interfere with the host response by modulating or disrupting the function of corresponding host genes [ 49- 51].
"If this disorder is not ended quickly, the attempt to paralyze the country could have consequences for jobs by disrupting the normal functioning of the economy," Mr. Sarkozy told his cabinet in remarks released by his office.
More suggestions(16)
by using the function
by disrupting the distribution
by disrupting the gene
by disrupting the development
by disrupting the time
by defining the function
by disrupting the hydrogen
by disrupting the incorporation
by removing the function
by disrupting the way
by disrupting the synthesis
by disrupting the recruitment
by perturbing the function
by disrupting the power
by disrupting the cell
by disrupting the body
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