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In addition, JTB and its orthologs likely represent a unique and ancient protein family since homologs could not be identified by direct sequence comparison.
In total, we identified 40 cells with anomalous sequence variation from a total of 7094 single cells by direct sequence comparison, although the negative controls included in these experiments consistently yielded no detectable amplification on 1.5% agarose gel.
Thus, we checked the 125 candidates further by direct sequence comparison to see if they match any annotated gene.
The required promotor data retrieval in this study was achieved in a manual, hand curated manner by direct sequence comparison.
The limited amount of genomic sequence that is currently available for the other chromosomes of RH precludes such an analysis by direct sequence comparison to DM.
For our phylogenetic analysis, we selected alpha-skeletal actins in several different species, or where that was not possible, an isoform most similar to alpha-skeletal actin by direct sequence comparison.
Similar(52)
Further elucidation of the genetic bases of the different levels of resistance is only possible by direct sequence comparisons of the seven resistant haplotypes.
By both direct sequence comparisons and SNP array genotyping, we found that one SNP locus (CCR1 641) had a high minor allele frequency (0.41) in the macaques derived from Indochina and Chinese breeding center, and yet no heterozygous individuals were detected, a striking departure from Hardy-Weinberg equilibrium.
However, some mapping problems needed to be addressed either by automated rules, direct sequence comparisons or manual analysis and annotation.
Consequently, previous results from direct sequence comparisons are partly misleading.
Gene impacts were considered both computationally, by looking at the resulting amino acid sequence, and by direct sequencing, in comparison among five human populations and with five closely related primate species.
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