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The necessary combination of voxel- and cluster-level thresholds is not assumed from theory but rather determined by direct permutation for each data set.
The necessary combination of voxel and cluster-level thresholds was not assumed from theory, but rather was determined by direct permutation for each data set, giving excellent Type II error control (Bullmore, Suckling, et al. 1999).
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In contrast, loci significant by naïve permutation for coat color were found on nearly all chromosomes.
The significance level of the whole experiment was also calculated by data permutation: for each permutation, the p-values were re-computed and the number of genes significant at the 0.01 level of the permutation p-value was annotated.
The significance of the observed association was inferred by repeating the permutations for a thousand times.
Such an optimization problem is solved by a permutation GA for each individual panel.
d LOD thresholds score determined by permutation test for each trait in each environment (P = 0.05).
Significance of gene conversion was determined by a permutation test correcting for multiple comparisons.
Multiple testing adjusted significant thresholds to the 5%-level were determined by Bonferroni-adjustment or by permutation test (50 000 permutations, to account for correlations between cognitive phenotypes).
Compared to direct formulaic calculation, random number generation is slow, making a repetition of 10,000 permutations for each time series pair a computationally intense operation (Table 2).
We computed the p-values for each weight value by 10000 permutations, by permuting the sample labels based on the permutation events.
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