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In contrast, a recent study has shown that Smad7 enhances DNA repair after radiation by direct interactions with the ATM DNA repair complex (Park et al., 2014).
These finding may indicate that NP-Pt were toxic to RBC by direct interactions with 2.4 pg of genetic material in chicken RBC [34].
The data suggest that transmembrane proteins can be taken up into COPII vesicles by direct interactions with the coat proteins and may play a structural role in the assembly of the COPII coat complex.
Moreover, RPL26 plays a role in enhancing p53 mRNA translation during the DNA damage response by direct interactions with both MDM2 protein and p53 mRNA [34].
In this model, Lbx1 would regulate the transcriptional output from a small number of the tabulated SSTF genes by direct interactions with their enhancers and these direct SSTFs targets would, in turn, regulate some of the other tabulated SSTFs, as secondary targets.
A second model proposes that TMD integration is facilitated by direct interactions with Sec61.
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"We have found a completely novel way in which endocrine-disrupting chemicals may affect human reproduction by direct interaction with human sperm," Professor Skakkebaek said.
TfR can be targeted by direct interaction with Tf displayed on the surface of NPs [41].
The assembly and activation of a mitochondrial channel is triggered by direct interaction with signaling molecules that promote cell death.
As a control, a direct test of MVP luminescence generated by direct interaction with AgNp was performed and no MVP emission was detected for concentrations used above.
Recent report indicated that FXYDs stabilize the active conformation of the Na+/K+-ATPase by direct interaction with this enzyme (Mishra et al., 2011).
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