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Most of the cell's heavy duty computation is done by direct interactions between the proteins.
For example, some may believe that prices reflect fundamentals whereas others may rely on empirical observations of past price trends.Crucially, agents' behaviour may be determined (and altered) by direct interactions between them, whereas in conventional models interaction happens only indirectly through pricing.
However, only recently has attention been directed to interference caused by direct interactions between luciferase and chemicals being screened [48], [51], [52], [57].
Second, all three proteins bind in the same general region of pre-40S ribosomes, as indicated by direct interactions between Nob1 and Rps14 [29], and the observation that the binding site for the bacterial homolog of Dim1 is adjacent to Rps14 [38].
This work also calls for careful chemical and biological characterization of drug leads obtained from chemical screens to avoid the identification of irrelevant chemical structures and to avoid the interference caused by direct interactions between the chemicals being screened and the luciferase reporter used in screening assays.
The globular assembly of the PHCCEx domain is constructed by direct interactions between each pair of the three subdomains.
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Moreover, Ag NPs could damage algal cells by direct interaction between NPs and algal cells [72] or the type of NPs coating could play a significant role.
This effect is at least partly mediated by direct interaction between SGK and Nedd4-2.
PAK1 has been reported to regulate the ERK pathway by direct interaction between PAK1 and Raf and MEK.
To test whether enhanced encapsulation by rCfLec-1 was caused by direct interaction between rCfLec-1 and hemocyte surface molecules, lectin-coated beads were pre-incubated with rat polyclonal antibody to block the surface.
Electron transfer is accomplished by direct interaction between the exposed His ligand and the quinone substrate.
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