The matrix tablets were prepared by direct compression of mixtures of drug and nanoparticles, and then the release properties, swelling properties and changes in molecular weight of PLGA during the release test were evaluated.
Indomethacin conventional compressed tablets were prepared by direct compression of the physical mixtures of the drug, carrier, coat, E-RL 100, and lubricant.
To emphasize the efficacy of LS system to improve IDM release from controlled colon targeted matrices, tablets prepared by direct compression of the physical mixtures of all the matrix components were subjected to in vitro release studies.
Cylindrical matrix tablets of 150 ± 0.2 mg weight and 3 ± 0.2 mm thickness were prepared by direct compression of either physical mixtures or complexes with a single punch tableting machine (EKO, Korsh, Germany), equipped with flat punches of 7 mm diameter at a compression force between 20 and 30 kN.
The mechanical disintegration was suitable for both tablets produced by direct compression and those compressed from granules.
Tablets obtained by direct compression of drug-diluent-matrix ternary mixtures prepared according to the experimental plan provided for by an asymmetric screening matrix, were tested for drug release properties using a USP paddle apparatus.
Lamivudine 300 mg/TDF 300 mg tablets were developed and optimized by D-optimal mixture design and produced by direct compression technique.
Both spherical crystals were combined and compressed into tablets by direct compression technique.
The aim of the present investigation was to prepare extended release film coated matrix tablets of cephalexin using binary mixture of two grades of hydrophilic polymer, hydroxypropyl methyl cellulose (HPMC), by direct compression method.
Matrix tablets were made by direct compression method.
Tablets containing caffeine anhydrate were prepared by direct compression at various compression force levels using different shaped punches.
