Sentence examples for by direct administration of from inspiring English sources
Because of the promise of recombinant simian virus 40 (rSvectorsctors, we tested their ability to deliver a transgene and to target a transcript for destruction by direct administration of the vectors to the liver of an animal model for human α1-antitrypsin (α1-AT) deficiency.
In these studies, ovary-specific Cre-recombinase expression was achieved by genetic means [22] or by direct administration of adenovirus encoded Cre-recombinase [23].
Its role as a potential pathogenic factor will now be thoroughly analysed both by direct administration of the protein to animal models and by analysing its internalisation in cells of infected patients.
As a complementary approach to these genetic studies, we also examined the effect of blocking myostatin signaling pharmacologically by direct administration of a myostatin inhibitor to Dysf −/− mice.
Infant motor development was assessed by direct administration of the Bayley Scales of Infant and Toddler Development 3rd Ed, Fine and Gross Motor Scales (BSID-M) [ 43] to the infants when they were six months old.
The use of endogenous omega-3 PUFAs electrophilic derivatives as drugs would offer several advantages including the possibility to increase their concentration via two routes, that is, by oral supplementation of the fatty acid precursor and by direct administration of the electrophilic compound [ 8– 11].
The purpose of the present research was to produce respirable engineered particles of ketoprofen lysinate, a non-steroidal anti-inflammatory drug able to fight lung inflammatory status by direct administration to the site of action.
Since there are no reported toxic effects of these plants, it is possible to obtain a similar in vivo effect by direct administration to ruminants.
We are currently devoting significant efforts toward the treatment of infectious diseases by the direct administration of antimicrobial-loaded SCKs(22) to the lung and bladder.
Regarding therapies based on SOD, several AD phenotypes in mice can be improved by the direct administration of SOD, and the dietary intake of Cu stabilizes SOD1 activity.
A way of circumventing these issues is represented by the direct administration of recombinant bacteria, acting simultaneously as cell factory and delivery system for pharmacologically active proteins.
