Sentence examples for by diminishing the function from inspiring English sources

We also observed that the therapeutic effects of Pam2IDG are improved by diminishing the function of tumor-associate macrophages (TAMs) and through the use of an IL10 receptor blocking antibody or a Cyclooxygenase 2 (Cox-2) inhibitor.

In humans, it is well accepted that 'vitamin A deficiency impairs innate immunity by impeding normal regeneration of mucosal barriers damaged by infection, and by diminishing the function of immune cells [ 23, 24].

Severe impacts are modeled by diminishing the land use sector contributions to production and service delivery as a direct function of storm severity.

Recently, prostaglandin I2 was shown to reversibly inhibit platelet function by diminishing the expression of platelet fibrinogen receptor and P-selectin, and to reduce heterotypic platelet-leukocyte aggregation during clinical hemofiltration [ 27].

In conclusion, chronic vitamin A deficiency altered the structure and functions of pancreas by diminishing the islet cells, possibly by inducing cellular stress-mediated apoptosis and decreasing SCD1-mediated oleic acid (C18 1) synthesis.

Moderate alcohol consumption further protects the heart by diminishing the tendency of the blood to form clots and improving the functioning of blood vessel linings.

"We have modified the ecosystems by diminishing the big predators.

Alternatively, there might exist tissue-specific proteins that bind the mutant ARS, leading to disease phenotypes by inhibiting the enzymatic activity, or by diminishing potential noncanonical functions.

None of the multiple possibilities can be dismissed (excessive DA synthesis, release or leakage; reduced re-uptake by diminished DAT function or levels); however, an enhanced DA catabolism (with a dynamic limit in HVA fate and its consequent accumulation) seems to be more likely.

The infection, Kainer said, was slowly diminishing the kidney's function.

This weakens immunological resistance and thus diminishes the barrier function of the intestinal mucosa [ 12].