Sentence examples for by diminished expression of from inspiring English sources

Activation of the COX VIa-H gene also was observed during differentiation of nurine myogenic cells in culture and was followed by diminished expression of the COX VIa-L isoform in maturing myotubes, as in the intact animal.

The observation of reduced fetal leukocyte trafficking and chemotaxis is mainly explained by diminished expression of leukocyte adhesion molecules and production of cytokines at this developmental stage [26 28].

This increased susceptibility to toxoplasmosis was not explained by diminished expression of IFN-γ, NOS2 and TNF-α in the brain and eye (Figure 6H).

Scarless, fetal wounds are characterized by diminished expression of pro-inflammatory IL6 and IL8 [ 52, 53].

We therefore conclude that downregulation of COX 2 and iNOS by L.obtusiloba extract is mediated by diminished expression of PPARγ.

Thus, downregulation of COX-2 and iNOS by L.obtusiloba extract is mediated by diminished expression of PPARγ and due to a reduced transcriptional activity of NF-κB.

Since germ cell development critically depends on Sertoli cells, defect in CFTR-dependent FSH-stimulated CREB activation in Sertoli cells could affect germ cell CREM activation and germ cell development as reflected by the diminished expression of a spermatid-specific marker, protamine-2.

These experiments clearly show that the increase of p21 and p16 in senescent cells is accompanied by a diminished expression of RAC3.

Similarly, the aberrant astrocytes that surround giant cells in "microtubers" are characterized by markedly diminished expression of EAAT1, EAAT2, and GS, proteins important for the uptake and metabolic conversion of glutamate to glutamine within astrocytes.

Most importantly, the epigenetic inactivation of PIWI-class protein genes (PIWIL1, PIWIL2, and PIWIL4) and its associated protein TDRD1 in human testicular tumorigenesis occurs in a molecular context characterized by a diminished expression of the piRNAs and the DNA hypomethylation of LINE1, a PIWI/piRNA target sequence.

Because the resistance to PGE2-mediated suppression could have been caused by the diminished expression of the prostaglandin E2 receptors (EP1 EP4) in HPK1 −/− T cells, we performed Western blot analyses on lymphocyte whole cell lysates prepared from wild-type and HPK1 −/− lymph nodes, using antibodies that recognize specific EP receptors.