Sentence examples for by difficulties in detecting from inspiring English sources
However, numerous case reports have associated hGISA with a poor response to glycopeptide therapy but studies of their clinical significance have been hampered by difficulties in detecting these strains in the diagnostic laboratory and a lack of confirmatory tests.
Development of improved gene delivery strategies is critical for application of effective gene therapies, yet evaluation of the effectiveness of these strategies is often hampered by difficulties in detecting transgene expression in real-time in vivo.
This could be challenged by difficulties in detecting carbapenemase producers, since MICs to carbapenems could be elevated but within susceptible range or even low, as described in Enterobacteriaceae and A. baumannii [ 19].
However these studies have been hampered by the lack of defined single antigens, particularly for S. haematobium, and by methodological difficulties in detecting responses associated with resistance to infection/re-infection in field studies of human populations [ 40, 41].
Such analysis, however, is frequently complicated by the difficulties in detecting the low abundant species co-eluted with more abundant ones.
However, the application of the chemical type gas sensor is limited by several disadvantages, such as the potential difficulties in detecting gases with low adsorption energies, the high working temperature (except for the CNTs based sensors), and the higher power consumption.
It is thought that the large differences in reported incidences is explained by underestimation in some studies due to the difficulties in detecting HL.
Considering these difficulties in detecting a minimal gene set by both the computational and experimental approaches, we adopted a different strategy.
Difficulties in detecting substantial G72 expression could potentially be accounted for by unstable mRNA species.
There are several diagnostic difficulties highlighted by our study, and a small study of 44 children has previously identified similar difficulties in detecting lung parenchymal changes using whole-body post-mortem CT [ 15].
