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In this study, we compared the poly(A) sites obtained by different sequencing technologies and found that deep-sequencing (454 and Illumina sequencing) revealed much more previously unannotated poly(A) sites.
Our results show that the combination of data obtained by different sequencing technologies can allow to recover relevant information of underrepresented organisms.
The tRNA gene content of the Illumina sequence contigs from T. aestivum group 5 chromosomes also exhibited the same pattern for all homeologous group 5 chromosomes, indicating that the abundance of tRNALys species is a shared phenomenon and is not an artefact caused by different sequencing technologies.
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Indeed, with the large amount of high-resolution data provided by the different sequencing technologies used in the 1000 Genomes Project, scientists could work toward assembling a detailed map of not only common variants but also rare variants and sets of variants within specific genomic regions suspected of contributing to disease.
The slight difference between stacking energy of mouse samples Wold data and Grimmond data might be caused by the different sequencing technologies.
Then we analyzed comparatively the sets of B. fulgida ORFs that were recovered by the different sequencing technologies; the recovered ORFs were compared with respect to the coverage pattern, and the percentage of covered amino acids (here called mapping).
To do this study, they used already available genomic data (183 metagenomic samples, obtained by different labs, using different sequencing technologies) to examine how nucleotide composition varied across phyla and environments (e.g., soil, water, and the human gut).
Our model can be applied to different sequencing technologies by appropriate settings of model parameters.
To compare reads generated with different sequencing technologies, we also performed the HTS simulation by generating virtual reads in base space (for example as in Illumina sequencing) rather than color space (like in SOLiD sequencing).
These genomes were generated with different sequencing technologies, coverage, and gene prediction software.
That project is intended to compare different sequencing technologies and document just the baseline variation in the human genome.
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