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As in the case of RB1, the underlying reason for the discordance caused by different detection regions among technologies and platforms may be associated with the degree of accuracy in the sequence information being varied at different regions due to the continuous discoveries of previously unknown SNPs and spliced variants.
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When the same target (HER-2) was detected in the same cDNAs with a different set of primers, targeting different regions in the gene sequence, and by different detection systems, results were not statistically correlated.
When the same target was detected in the same cDNAs with a different set of primers, targeting different regions in the same gene sequence (HER-2), and by different detection systems, results were not statistically correlated.
For occasions when regions called by different triPOD detection methods overlap, rules have been created to prioritize, combine, and splice such regions.
Using different detection spectral bands, spatially resolved regions attributed to different-sized PAHs are presented.
However, none of these studies compared the peak regions identified using different detection programs.
This observed difference may be due to the different detection protocols employed by different researchers.
The key functions and proteins encoded by different regions of the HPV genome that are relevant for designing detection assays are shown in Figure 1.
Correct detection: regions labelled by both methods.
In a nutshell, the detection regions are represented by a set of slightly modified hypercones.
Those rules are voluntary, however, and are followed to different extents by different regions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com