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The management of such systems is carried out with efficient algorithms and is only controlled by different computational methods (Batool and Niazit 2015).
To benchmark the predictions obtained by different computational methods we used both "Cost Curves" and ROC analyses.
Moreover, each miRNA target is associated with gene ontology and pathway terms, together with the target site information and regulating miRNAs predicted by different computational methods.
Because of the variability provided by different computational methods, in silico predictions of variant pathogenicity were not used to evaluate missense PPVs.
The sequence counts in this scan generally agree with previously published kinome analyses, though because these and most previous annotations are produced by different computational methods there is occasional disagreement over the classification of more divergent sequences lacking clear orthologs in model organisms.
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We investigated the nature of four sets of CTFPs (predicted by four different computational methods, see Table 1 and Methods) by means of the analysis of their roles in two distinct biological networks (the protein interaction network and the regulatory network).
Nowadays frontier molecular orbitals analysis is well known to explain the reactivity of compounds [21] by using different computational methods.
The methods require either sequence or structural information and present different limitations, their performance depending on the impact on structural stability or intermolecular interactions of the mutation; methods are often complementary in approach to others (43) implying that overall prediction quality could be improved by combining different computational methods.
Because the wealth of information contained in protein interaction networks and regulatory networks has proven highly effective in elucidating functional relationships between proteins, we compared different sets of cooperative transcription factor pairs (predicted by four different computational methods) within the frame of those networks.
software by the use of nine different computational methods for estimation of log P.
High-confidence pairs (HCP) are those that were predicted using multiple sources of information or by at least two sufficiently different computational methods.
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by different computer methods
by standard computational methods
by additional computational methods
by different computational techniques
by previous computational methods
by current computational methods
by different computational descriptors
by numerous computational methods
by different computational methodologies
by conventional computational methods
by appropriate computational methods
by automated computational methods
by many computational methods
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