Since CXCR3 is differentially expressed by different cell types, which also differs between mouse and man, translating experimental and clinical data is challenging.
Olfactory receptors are expressed by different cell types throughout the body and regulate physiological cell functions beyond olfaction.
Walisser, J. A., Glover, E., Pande, K., Liss, A. L. & Bradfield, C. A. Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types.
Endothelin-1 (ET-1) and endothelin-2 (ET-2; Trp6Leu7ET-1) are expressed by different cell types, but are considered to display identical pharmacological properties on endothelin receptors.
Exosomes represent a new family of bioactive nanovesicles (30 100 nm in diameter) secreted by different cell types whose appealing features can be exploited for designing vaccines in the context of several human diseases.
Nowadays, it is well established that this protein can be expressed by different cell types, aside from its expression in Tregs, which include normal [21] and tumor [20, 43] cells.
Histamine's pleiotropic actions were acknowledged since its discovery and since the 1960s attributed to the secretion by different cell types (Table 1) and the differential tissue expression of several receptors (Table 2, [6, 7]).
PTX3 is an acute-phase inflammatory mediator produced by different cell types [3, 14] that exerts protective effects in experimental acute lung injury, closely resembling those of MSCs [15].
