Sentence examples for by different array platforms from inspiring English sources
Previous clinical studies have demonstrated a higher CNV diagnostic yield in syndromic CHD than that in isolated CHD, but these studies were all done separately for either syndromic CHD or isolated CHD by different array platforms (Table 4).
Differences between the two studies may be explained by usage of different array platforms, data analysis methods and cohort composition.
To obviate fundamental difference inherent in different array platforms, we focused mainly on gene expression data based on Affymetrix oligonucleotide arrays, particularly more advanced platforms such as U95Av2 or U133 series.
To obviate fundamental difference inherent in different array platforms, we focused our analysis on gene expression data from NCI60 cell lines and primary tumors (Table 1) based on Affymetrix U95Av2 oligonucleotide array platform.
An essential challenge, in fact, is given by the efficient integration of gene expression data on the same issue generated by different research groups using different array platforms and experimental conditions.
The availability of publicly available gene expression datasets have opened up new challenges especially for the integration of data generated by different research groups and different array platforms with the purpose of obtaining new insights on the biological process investigated.
We have investigated the genome-wide profile of structural variation on pooled samples from the three populations studied in the HapMap project by comparative genome hybridization (CGH) in different array platforms.
Although direct comparison is difficult, as CNV region boundaries identified by arrays cannot be well defined and different array platforms use probes located in different regions, we have estimated to what extent our results matched with previous data deposited in the database of genomic variants (DGV - [55]) by evaluating reported frequencies of overlapping CNVs (Table S3).
Such a limitation of SEP or similar classifier is presumably caused by technical variations between microarray datasets, especially different array platforms.
Genomewide array analysis was performed before ANKRD11 analysis in all patients using different array platforms according to local protocols by the referring institutions.
We experimentally demonstrated variation in CGH results by repeating the CGH array using a second reference genome and two different array platforms, demonstrating the effect the reference DNA has on the outcome of a CGH experiment (Supplementary Table 4).
