An additional disadvantage of symptom screening and especially prolonged cough, is the wide variation in accuracy observed between studies [ 5], which was in part explained by differences in region and population HIV-prevalence.
The difference in the quantity of transcripts produced by the rpl6 genes might be caused by differences in promoter regions because their 5'-noncoding regions differ from a point near the center of the intron (Fig. 1A).
This is not explained by differences in coding region length (Supplementary Material, Figs S1 and S2).
In Arabidopsis thaliana, we denote levels of structural divergence between duplicated genes by differences in coding-region lengths and average exon lengths, and the number of insertions/deletions (indels) and maximum indel length in their protein sequence alignment.
Structural divergence between duplicated genes was measured by differences in coding-region lengths and average exon lengths, and the number of indels and maximum indel length in their protein sequence alignment.
When measured by differences in coding-region lengths and average exon lengths and the maximum indel length, structural divergence between duplicated genes shows the following trend: WGD < tandem < proximal < transposed (comparisons between consecutive gene duplication modes are significant at α = 0.05, Wilcoxon test).
This divergence might be explained by differences in neuroplasticity between brain regions, which in the context of skill acquisition can produce opposite volumetric changes in the cortex and basal ganglia (Kloppel et al., 2010).
Thus, the excess of uORFs in alternative versus constitutive regions of 5'UTRs is not caused by differences in nucleotide compositions of these regions.
This method has the advantage over fMRI in that categorization and recognition can be disambiguated by differences in both timing and region.
If the cofactor hypothesis concerning the timing of the response of NF-κB-dependent genes has some merit, as it is claimed in Paszek et al. [ 7], then it is likely that the differences in timing are reflected by differences in the structure of promoter regions of genes in different categories.
