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However, each disease differs from one another by differences in protein deposition or biochemical signature, and inclusion morphology and distribution [ 15].
Thus, the observed differences in dN/dS cannot be explained by differences in protein length or absolute expression levels between genes of different categories.
Differences in histology are paralleled by differences in protein profiles, as reflected in the clustering analysis using the spectral counts as measures of protein abundance (Figure S1).
We explained such data discrepancy by differences in protein content of the compared strains.
For two of the proteins there was a significant difference in the failure curves between the strata predefined by differences in protein abundance measurements.
We first tested the hypothesis whether systemic inflammation in COPD would be reflected by differences in protein expression compared to neutrophil protein expression from healthy control subjects.
Similar(50)
In such scenarios, complexity and variability of symptoms associated with RNA repeat-mediated mechanisms could be explained by differences in protein-binding properties of different repeats and heterogeneity of protein environment in different tissues.
We performed TBLASTN searches (on the criteria of an E-value cutoff of 1e-5, and minimum aligned sequence length coverage of 50% of a query sequence) of each of the 29 strains' proteomes against whole nucleotide sequences of all the other strains to avoid artefacts caused by differences in protein-coding sequence prediction [ 8, 48].
We were not able to explain the variation in aggregation rates by differences in known protein properties such as enzyme activity, protein thermostability, mutation position or degree of change in protein charge.
The decrease in Est1 telomere association could not be explained by differences in Est1 protein level or immunoprecipitation efficiency in Ku mutant strains as Est1 protein levels were equivalent in input and IP samples.
This result suggests that at least some of the variation in total IDH activity is explained by differences in IDH protein quantity.
More suggestions(16)
by differences in linkage
by differences in grain
by differences in quality
by differences in disease
by differences in enzyme
by differences in inclusion
by differences in solution
by differences in productivity
by differences in tax
by mistakes in protein
by differences in peak
by changes in protein
by differences in rice
by inconsistencies in protein
by differences in solubility
by differences in elevation
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