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Antibiotic resistance is a growing problem worldwide, with 10% of Streptococcus pneumoniae isolates recorded as non-susceptible to penicillin in 30 countries in 2007. 1 There is wide variation in antibiotic prescribing for ambulant patients in Europe. 2 We do not know if this variation is explained by differences in presentation of illness or to which conditions it applies.
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The poor recognition of synthetic peptides comprising this region of fibrinogen by RA sera in previous studies [ 4, 9] might be explained by differences in the presentation of the epitope(s) by (partially) different peptides.
To assess, whether for faces the group differences found in reaction times can be explained by group differences in presentation times, again nullmodels were constructed for both dependent variables but this time without a prior transformation, and the respective residuals, as well as the difference in residuals was calculated.
The differences in latency between the N400 elicited by words and chords can be explained by differences in modality of presentation (auditory vs visual), as previous studies have shown earlier N400 onset when targets were presented auditorily compared to visually [13].
This is only partly accounted for by differences in stage at presentation and morphological type.
We further observed that this difference was limited to those over 70 years and could not be accounted for by differences in stage at presentation, comorbidities, treatment, SES or remoteness of residence.
Later diagnosis might be caused by differences in symptoms and clinical presentation or a more aggressive biological tumor behavior.
37 This finding may potentially be explained by differences in binding ability, antigen presentation or functional capabilities.
Variation in antibiotic prescribing that is not warranted by differences in illness and clinical presentation may increase selection of resistant organisms, contributing to the problem of antibiotic resistance.
The Estimation of Causal Effects by Difference-in-Difference Methods.
While we felt that there is no evidence that shows any differences in presentation by gender, further studies are required to determine if similarly high diagnostic ascertainment can be achieved in other age groups.
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