This ddPCR method provides the ability to scale the number of partitions by combining replicate wells to resolve fine copy number differences in heterogeneous mixtures and could foreseeably form the basis of more efficient diagnostic tests.
Systemic lupus erythematosus (SLE) is a highly heterogeneous disorder, characterized by differences in autoantibody profile, serum cytokines, and clinical manifestations.
It is a heterogeneous disease, as reflected by differences in severity, pathogenesis and treatment outcome.
D is a diagonal matrix with d ii =1/ w i and [ 29, 30], w i is a weighting factor that accounts for heterogeneous residual variances caused by differences in, the reliability of the i− t h DRP [ 3].
The difference in findings may be explained by our larger and more heterogeneous sample of participants, and possibly by differences in how physical activity was assessed.
Duchenne muscular dystrophy (DMD) is a clinically heterogeneous disorder of at least 4 clinical subphenotypes characterised by differences in the severity of muscle and brain dysfunction (Online Mendelian Inheritance in Man (OMIM) 310200) [1].
Acute myeloid leukemia (AML) is a heterogeneous disease with respect to clinical picture and therapeutic outcome, partly reflected by differences in cytogenetics and molecular genetics.
Open image in new window Fig. 1 Static models, a permeability differences in areal heterogeneous model, b permeability differences in vertically heterogeneous model.
Because of these differences in values, heterogeneous governance structures have been implemented.
Results showed elevated voltage differences between layers in heterogeneous experiments compared to equivalent homogenous experiments.
