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In both studies, randomization was stratified by diabetic status and screening TG level (≤250 mg/dL or >250 mg/dL).
Fisher and colleagues [ 27] have stated that there is a bidirectional relationship between periodontal disease and CKD, an association mediated by diabetic status and hypertension.
Our a priori analysis objectives also included examination of the association between statin use and mortality separately among men and women, as well as by diabetic status and age (<65 or ≥65 years) at cohort entry.
Our a priori analysis plan called for examination of the association between statin use and mortality separately by race and sex, as well as by diabetic status and age (<65 or ≥65 years) at cohort entry.
Post hoc analysis about factors that affect point accuracy including Table S1 with results from the linear mixed model, Table S2 with accuracy metrics stratified by diabetic status, and Figure S1 with Bland-Altman plot with bias and limits of agreement (bias ± 1.96 standard deviation of the bias), glucose prediction errors, and Clarke error grid analyses stratified by diabetic status.
Additional analyses stratified patients by mean BG during ICU stay using increments of 80 to 110 mg/dL, 110 to 140 mg/dL, 140 to 180 mg/dL and ≥ 180 mg/dL, as well as by severity of illness, using APACHE II scores, and by diabetic status and diagnostic category.
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Mean levels of the different glycemic markers differed substantially by diabetic status (Tables 2 and 3).
Correspondingly, our observation of effect modification by diabetic status in the association between traffic pollution and parasympathetic tone may be due to a higher likelihood of diabetics to have decreased parasympathetic tone than non-diabetics [ 25] and/or to their greater baseline oxidative stress, which has been shown to mediate the autonomic effects of particles [ 26- 28].
Pre-operative plasma Omentin levels were not significantly different in men vs women and were not affected by diabetic status.
Table 2 details important clinical characteristics and glycemic control metrics of the study cohort for TIR-hi and TIR-lo, stratified by diabetic status.
Our observation of effect modification by diabetic status in the associations between the cumulative effect and 4 hr before ECG measurement lag effect of BC and NO2 exposure and prolonged QTc for the QCDL and hourly lag models may be due to a higher likelihood of persons with diabetes to have prolonged QTc than those without diabetes.
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