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Here, we improve the versatility of this method by developing a transgenic system that expresses Cas9 in the Drosophila germline.
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We demonstrated that mutations caused by the transformation event used in developing a transgenic OSCR11 rice line were mainly induced during the cell culture step and were almost indistinguishable from those associated with somaclonal variation, suggesting that there was an undetectable level of genomic damage, if any, caused by Agrobacterium infection other than T-DNA insertion.
A British team now confirms and improves upon previous work by developing an even more sensitive transgenic zebrafish biosensor for assessing potential endocrine disruptors [ EHP 120 7):990 996; Lee et al.].
Above information provides a possible strategy to develop a transgenic model of ovarian carcinoma [39].
It takes on average six months to develop a transgenic potato line using RNAi constructs.
In conclusion, the current study provides good basement and helpful information for commercial large-scale production of tanshinones in the roots of Salvia by developing ATM transgenic lines with altered phenotype.
Chodosh and colleagues used the same conditional system to examine the requirement of continued Wnt1 expression in the maintenance and recurrence of mammary cancers by developing double transgenic mice with conditional expression of Wnt1 (MTB/TWNT mice) [ 21].
Further, we characterize an Aldo-keto reductase (AKR) by developing transgenics in tobacco and rice susceptible genotype Telahamsa.
To evaluate the axon outgrowth of RGCs for Del605 607 mice, we first developed a double transgenic mouse by mating Del605 607 mice with Thy1 promoter-driven cyan fluorescence protein (Thy1-CFP) transgenic mouse, which enables visualization of RGC with CFP filter.
We have recently developed a novel transgenic mouse model that over-expresses Pol β.
This is usually circumvented by developing large populations of transgenic lines, each derived from the first shoot to regenerate from each transformation event.
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