Sentence examples for by determining the affinity from inspiring English sources
The role of apoptosis in affinity maturation was investigated by determining the affinity of (4-hydroxy-3-nitrophenyl)acetyl (NP -specific aNP -specificing cells (AFCs) and serum antibody in transgenicellse thAFCsverexpress anduppreserumof antibodys, Bcl-xL, in transgenic comicethatt.
We performed mutational analysis within CDR3 to substantiate the role of CDR3 in gp120 interaction by determining the affinity of the D7 mutants in comparison to the wild type using surface plasmon resonance.
Biological activity and receptor binding properties were examined by measuring the IL-4 dose dependency of TF-1 cell proliferation as described (Tony et al., 1994) and by determining the binding affinity of the recombinant IL-4 protein to its high-affinity receptor IL-4Rα via surface plasmon resonance as published (Shen et al., 1996).
Regarding the strength of interaction between two molecules, we can assess it by determining the value of binding affinity, K A. Among these five mutant aptamers, the Seq15_12_35 had the largest K A value, and Seq16 had the worst K A value.
Purified samples of scFv, Fab, scFab and scFabΔC were analyzed by surface plasmon resonance (SPR) to determine the affinity of the different antibody variants.
The abilities of these bis amidoxime)s to complex uranyl cation in water were evaluated by determining their affinity constants and thermodynamic parameters by means of Isothermal Titration Calorimetry (ITC).
The improvement in performance of this 2D-TFC/LC MS approach over the conventional approach has been demonstrated by determining affinity-selected ligands of the target proteins acetylcholinesterase and butyrylcholinesterase from a small library with known binding affinities and a steroidal alkaloid library composed of structurally similar compounds.
Thus, although BLI kinetic analysis revealed a distinguishable kinetic trend between class 1 and class 2 mutations, the disease class associated with HIF-2α mutations could not be absolutely predicted solely by determining affinity for pVHL due to outliers like A530V.
This trend was attributed to a dominating role played by desolvation in determining the relative binding affinity.
By determining affinities of these ligands for various regulatory state SFK mutants, one can determine the influence of intramolecular interactions on ATP-binding site conformation.
The nature of the disease caused by these arthropod-borne viruses (arboviruses) is determined by the affinity (tropism) of each virus for specific organs.
