Sentence examples for by defects in several from inspiring English sources

Severe mongenic hypercholesterolemia can be caused by defects in several different genes (7).

Cystinosis is characterized by defects in several tissues, especially the kidneys and eyes, but also affects other organs (Nesterova & Gahl, 2008).

In the limb, the absence of Fz3 leads to a specific stalling defect among LMCL axons that is distinct from the phenotypes produced by defects in several other signaling systems active in limb axon guidance.

It is caused by defects in any of several genes that code for proteins, such as collagen, that link the top and bottom layers of skin.

Fourth, the inner ear is extremely sensitive to even modest changes in signaling, as evidenced by the presence of defects in several heterozygous mouse lines [46], [58].

Moreover, AQP4 down-regulation was observed in human patients affected by Limb Girdle Muscular Dystrophies (LGMDs) [13], in which defects in several isoforms of sarcoglycan (SG) occur.

Mutations in lin-14 cause cell lineage defects in several cell types.

The metabolic signature of cancer cells correlates with defects in several signaling pathways.

Several diseases are caused by defects in the protein secretory pathway of the cell, particularly in the endoplasmic reticulum (ER).

Several human diseases are characterized by defects in the synthesis and the secretion of the ApoB-containing lipoproteins.

TRANSLATIONAL IMPACT Clinical issue Ciliopathies are a class of diseases caused by defects in primary cilia, organelles that coordinate the transduction of several cellular signaling pathways.