Sentence examples for by deep sequencing methods from inspiring English sources

It has now become a routine task to map epigenetic marks and chromatin structure by deep sequencing methods.

Polymorphic markers would have been considerably increased by deep sequencing methods of the AFLPs [ 40].

Small RNAs are best discovered and measured by deep sequencing methods that have high sensitivity and specificity [ 23- 25].

It is not possible at present to sequence the ssRNA population to saturation even with deep sequencing methods, so we cannot yet rule out that such an organisation is an experimental artefact caused by incomplete sampling of the ssRNA population.

Deep sequencing methods have revolutionized genetic analysis [2].

An example of deep sequencing methods providing extremely high resolution and sensitivity over Sanger sequencing is the use of the technology to examine within-host diversity of Plasmodium infections by amplicon sequencing.

However, many deep sequencing methods have inherent error rates, which may obscure somatic mtDNA mutation loads.

Wu and colleagues [ 57] applied deep sequencing methods on blood of patients with primary stage II or III breast cancer to indicate the miR-375 prognostic value and validated these findings in an independent cohort by using qRT-PCR.

Ideally, our study should be replicated using deep sequencing methods along with analysis of DNA polymorphisms at multiple genes.

RNA was further processed, and analyzed by 3′READs, a deep sequencing method to analyze poly(A)+ RNAs using 3′ end regions, as described (Hoque et al., 2013) with some modifications for RNA fragmentation.

In 20% of the experiments we failed to detect in situ signal ('no signal') although the transcript was detected at least at one time point by at least one deep sequencing method.