Sentence examples for by decreasing transcription of from inspiring English sources
By decreasing transcription of components of cluster synthesis machinery, both iron utilization and regulation of iron uptake are impacted, contributing to the sideroblastic phenotype.
Corticosteroids normally reduce inflammation by decreasing transcription of activated inflammatory genes, which occurs at least in part by recruitment of histone deacetylase-2 (HDAC2) [ 235].
PPARα agonists control HDL cholesterol production by increasing transcription of apoA1 and, also, by decreasing transcription of serum amyloid A, increasing the anti-inflammatory HDL cholesterol effect (4, 5).
Myogenic hypermethylation from intragenic or intergenic locations could exert its effects on enhancers by decreasing transcription of the enhancer itself as well as by repression of canonical promoters of protein-encoding or lncRNA genes [ 76, 77].
Therefore our findings could be interpreted in a way that ENV1 dampens G-protein signalling during early light response by decreasing transcription of phlp1, gnb1 and gng1 in order to provide resources for protective measures.
Taken together, this suggests that the decrease in apoM levels during acute-phase reactions is mostly explained by decreased transcription of the apoM gene, in analogy to the actions of the other negative acute-phase apolipoproteins.
The cell cycle is known to lengthen as cells begin to differentiate in some contexts, and cell cycle progression depends on rapid protein turnover; it is possible that reduced efficiency of this process, predicted by decreased transcription of proteasome subunit genes and validated by aggresome accumulation, contributes to cell cycle lengthening.
In particular, the apparent down-regulation of the entire glycolytic pathway that was suggested by the strongly decreased transcription of the corresponding genes during mid-stage meiosis was not confirmed by enzymatic measurements.
In vitro, PPARγ agonist reduces intercellular adhesion molecule-1 (ICAM-1) expression in activated endothelial cells, inhibits production of proinflammatory cytokines (TNF-a, IL-6, and IL-1β) by activated monocytes, decreases transcription of monocyte chemoattractant protein, and significantly reduces monocyte/macrophage homing to atherosclerotic plaques [ 3- 5].
Expression analysis reveals that mutating the Abf1 binding site decreased transcription of RPS28A by about threefold, CNB1 and ARO3 by eightfold, and RPL3 surprisingly not at all.
