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Type 1 interferons, which include interferon alpha, have been shown to have a deleterious effect during L. monocytogenes infection by decreasing the viability of infected macrophages [23,24].
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Jak inhibitor tofacitinib was also adopted in our research which showed that tofacitinib at the concentration of 0.25 μM reversed sorafenib resistance by decreasing the cell viability while it alone did not impact cell viability).
Crizotinib abrogated LX2 coculture induced sorafenib resistance by decreasing the cell viability).
A recent study found that use of cell phones adversely affects the quality of semen by decreasing the sperm counts, motility, viability and morphology.
The expression of the transcription factor encoding gene HAA1 was found to markedly decrease the duration of the adaptation period of a yeast cell population suddenly exposed to toxic concentrations of acetic acid, by decreasing the loss of cell viability that occurs during this phase of growth latency [ 5].
However, if consumption by earthworms decreases the viability of other orchid seeds as much as it does for G. pubescens, it seems unlikely that earthworms moving seeds to the surface will result in significant subsequent germination.
In accordance, lowered IGFBP5 expression by RNA silencing decreased the viability of LX2 cells.
Probably a proliferating state renders tumour cells more sensitive to chemotherapy: structural damage during DNA synthesis induced by anthracycline exposure decreases the viability of newly formed cancer cells (Collecchi et al, 1998; Billgren et al, 1999; Makris et al, 1999).
Knocking down the expression of TRIM29 by short-hairpin RNA interference decreased the viability of keratinocytes after UVB exposure.
For WM983B cells, however, 100nM AZD7762 alone decreased the viability by 90%% and co-treatment with MK775 did not enhance the effect.
However, the addition of cargo to Lipofectamine 3000 decreased the viability by ~18% (P = 0.0094; nontransfected control, P < 0.001; vehicle only control).
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