Sentence examples for by decreasing the secretion from inspiring English sources

We have previously shown that estrogen inhibits elastolytic activity in VSMC cells by decreasing the secretion of matrix metalloproteinases (MMPs).

These data demonstrate that rosiglitazone mimics insulin action in cultured human hepatocytes by decreasing the secretion of TAG and ANGPTL3 in a dose-dependent manner.

EP is an effective anti-inflammatory agent and shows its efficacy by decreasing the secretion of proinflammatory proteins such as TNF- α and IL-6.

Moreover, it has been shown that green tea polyphenols can exert anti-inflammatory properties by decreasing the secretion of interleukin-6, interleukin-8, and C-C motif chemokine ligand 5 (CCL5) by P. gingivalis-stimulated gingival epithelial cells [ 13].

IMiDs also decrease the development of regulatory T cells in MM. 19 In addition, lenalidomide inhibits myeloid cell-mediated inflammatory function by decreasing the secretion of IL-6, TNFα, and IL-10.

This study demonstrated that microspheres were able to prevent the IL-1β induced IL-1β inducedtype II collagen and proteoglycan in OA cartilage breakdownsing the secretiof of IL-1β, leading typehe deceleratIIn of OA progression.

Based on our findings, it can logically be argued that octacosanol directly or indirectly acts on the hypothalamic pituitary adrenal (HPA) axis to lower the stress level by decreasing the corticosterone secretion.

Lithium may also exert its therapeutic effects by decreasing the sensitivity of melatonin secretion to nocturnal light exposure (Hallam et al. 2005).

126 Nitric oxide was shown to mediate cytokine-induced inhibition of glucose-stimulated insulin secretion by decreasing the mitochondrial oxidation of glucose to CO2, thereby preventing ATP accumulation.

miR-96 also downregulates insulin secretion by decreasing the expression of nucleolar complex protein 2 (Noc2), a Rab GTPase effector required for insulin exocytosis, as well as by upregulation of granuphilin, although this appears to occur via a distinct mechanism not involving Onecut-2.

However, triphenyltin exposure has been shown to cause hyperglycemia in rabbits and hamsters, possibly due to inhibitory effects on insulin secretion by decreasing the glucose-induced rise in intracellular Ca2+ in pancreatic beta-cells, as shown in triphenyltin exposed hamsters [ 95, 96].