Sentence examples for by declining expression of from inspiring English sources

It is noteworthy that in sepsis neutrophils often fail to move to the infectious site because their chemotaxis is reduced by declining expression of CXCR2, an essential chemotaxis receptor, but A2MG prevented this decline.

Unlike CD4-dependent TCR signalling, which is disrupted during MHCII-specific positive selection in 4in8 mice by declining expression of Cd8-encoded CD4 coreceptor proteins, CD4-independent MHCII-specific TCR signalling persists throughout positive selection.

The predominant expression patterns of these genes from 1 to 24 hours predominantly revealed rapid up-regulation, followed by declining expression at 24 hours.

IFN- γ treatment declined expression of LXR- α by 34.6 ± 3.2% versus control), TNF- α downregulated mRNA and protein level of LXR- α to 41.2 ± 2.5% and 53.2 ± 8.7% (P < 0.01, n = 3), respectively.

Disorganization of the sarcomeres and dedifferentiation of cardiomyocytes illustrated by the declining protein expression of α-sarcomeric actin is a programmed cell survival mechanism [ 26] which is also needed to enable proliferation [ 5].

It has been demonstrated that biomarker expression may be modified by declining kidney function.

Furthermore, in HeLa cells BA (300  μ M) was shown to stimulate the MAPK pathway in a bell-shaped fashion, with an initial induction of P-MEK1/2 and P-ERK1/2, followed by a decline in expression of P-MEK1/2 over time.

The resulting inhibition of Wnt signaling within sorted TECs was confirmed by the expected decline in expression of known Wnt target genes including Axin 2 and c-Myc, although a decline in Wnt target genes could also be explained by a loss of specific TEC subsets that differentially express these genes.

First, given the previously found decline in empathy by GPs over time, we expect to find a decline in expression of concerns or cues to underlying concerns by patients during recent consultations.

VDIPEN expression was decreased, but this was not reflected by declined MMP production, suggesting that IL-13 interferes at the level of activation of pro-MMPs.

By contrast, gene expression of mtDNA-encoded subunits declined significantly in HepG2 cells treated with this fatty acid (Fig. 2B).